In 8° (200x130 mm); pp. XX including the title page, 224, (2), 1 beautiful copperplate engraving by Giuseppe Manzoni depicting thirteen surgical instruments, placed at the end of the volume, folded; wood-engraved initials, with woodcut headpieces and tailpieces. Bound in a semi-rigid, full contemporary parchment binding. First edition of one of the earliest and most famous treatises on ophthalmology printed in Italy. Excellent copy on heavy paper with a watermark; a faint stain along the lower margin persists throughout the volume. Abrasion on the front cover of the parchment. Ref: missing from Wellcome; De Renzi V, p. 877; Blake p. 48.