In 4° (mm 250x180). Editorial mark in silography on title page by Luca Antonio Giunta with motto “Flos iustitia”; 22 unnumbered papers, including life and author's portrait, 169 numbered papers, 1 unnumbered endpaper with register and editorial mark repeated with date MDLXXIIII (colophon of previous edition), missing ab origine endpapers up to 213 indicated in bibliography. Elegant editorial layout with wood-engraved headpieces and endpapers, many diagrams in silography in the text, printed margin notes. Binding in full antique though later semi-rigid vellum, manuscript title to spine, splash cuts. Important collection of the works of the author (third edition, reprint of the first of 1555), scientist and man of letters from Verona (Verona,1476/78 - Incaffi 1553), physician to the Council of Trent, colleague and friend of Copernicus and other important scholars of the 1500s, including Gesner; this collection explicates the multifaceted nature of Fracastorian interests grouped into scientific, medical and philosophical activities.The first book of the work is Homocentricorum, sive de stellis followed immediately by De diebus criticis libellus; it deals with astronomical studies on the homocentric spheres, studies that Fracastorus took up from his friend G.B. Dalla Torre, the main source of his own cosmological researches, where he describes the celestial motions and represents them in silographic diagrams in the text; there is a description of the first idea of the telescope, used for the observation of the stars; this is followed by De sympathia et antipathia rerum a necessary work and an introduction to the theory of contagions treated in De contagione, contagiosismorbis et eorum curatione. The three philosophical dialogues: Naugerius sive de Poetica, Turrius sive de intellectione, Fracastorius sive De Anima, the latter unfinished were never published prior to the edition of the opera omnia. De Vini Temperatura Sententia concludes; the last treatise Syphilidis, sive de morbo Gallico, libri tre; the two-book poem Ioseph and Carmina in this copy were not included ab origine. Very good copy showing slight marginal haloes to title page and external speckling to the next three papers, some other slight haloing and slight reddening to a few pages at the end of the tome. Riccardi, Italian Mathematical Library, I, 482. Sallander, Biblioteca Walleriana, 3169; Adams F-819; Brunet II, 1363; Camerini II, 767; Graesse II, 623